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Allegro Ophthalmics to Present the Results of Its ALG-1007 Ex-U.S. Trial for Dry Eye Disease at the 2019 ASCRS•ASOA Annual Meeting. April 30, 2019 GMT. SAN JUAN CAPISTRANO, Calif.--(BUSINESS WIRE)- …

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The Option payment totaling $50 million would be made in two tranches, with the first payment of $10 million upon signing. 2019-04-25 · Allegro Ophthalmics has added ALG-1007, a new anti-integrin drug candidate for the treatment of dry eye disease, to its portfolio, the company announced in a press release. The topical agent is under evaluation in a phase 2 study outside of the U.S. and is the company’s first exploratory drug not in the retina space. 2019-05-10 · SAN DIEGO — At the American Society of Cataract and Refractive Surgery meeting, Eric D. Donnenfeld, MD, discusses ALG-1007, in development from Allegro Ophthalmics, a new small peptide anti Bausch Health anticipates that Allegro’s ophthalmic assets will complement its portfolio of AMD products. Bausch Health CEO and chairman Joseph Papa said: “If approved, risuteganib may be the first treatment indicated to help reverse vision loss due to dry AMD and would address a significant unmet medical need affecting millions of people globally.” 2019-05-17 · ALG-1007 also was well tolerated, with no drug-related adverse events. The trial included 40 eyes of 21 patients diagnosed with dry eye for at least 6 months. Patients were assigned to one of four doses, 0.125%, 0.25%, 0.4%, and 0.6%, in a lubricating ophthalmic topical solution.

ALG1007. Glycyl-glycine. NH₂CH₂CONHCH₂COOH. M.W. 132.12. Assay : >= 98%, Diglycine, Gly-Gly, Glycyl-glycine. MB Grade. 10 gm. 850. 100 gm. 6050.

Risuteganib ( RSG; also known as Luminate, ALG-1001, Allegro Ophthalmics, LLC, San Juan  1005. Taiwan BSMI RoHS declaration. . .

ALG1007. Glycyl-glycine. NH₂CH₂CONHCH₂COOH. M.W. 132.12. Assay : >= 98%, Diglycine, Gly-Gly, Glycyl-glycine. MB Grade. 10 gm. 850. 100 gm. 6050.

ALG-1007 was well-tolerated with no drug-related adverse events, even at the highest dose, and there was no reported blurring of vision or ocular irritation, even at the time of application.

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ALG-1007 is a topical integrin regulator in development for potential use in patients with dry eye disease. ALG-1007 demonstrated a strong signal in an ex-U.S. proof-of-concept clinical trial in which it showed a dose response curve and that it was generally well-tolerated.

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Allegro Ophthalmics to Present the Results of Its ALG-1007 Ex-U.S. Trial for Dry Eye Disease at the 2019 ASCRS•ASOA Annual Meeting. April 30, 2019 GMT. SAN JUAN CAPISTRANO, Calif.--(BUSINESS WIRE)- …

2019-04-25 · Allegro Ophthalmics has added ALG-1007, a new anti-integrin drug candidate for the treatment of dry eye disease, to its portfolio, the company announced in a press release. The topical agent is under evaluation in a phase 2 study outside of the U.S. and is the company’s first exploratory drug not in the retina space.

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